Photo ablation / activation / ...

Spot and patterns


With the Firefly system, you have one spot, fired with a click of the mouse. Adding the Geo gives the possibilty to create patterns or geometrical shapes for illumination of your sample.

Modular scanner-based and DMD-based pattern or spot illumination systems for your microsope.


Define the area(s) where you need the light for e.g.

          -bleaching, 


          -uncaging, 


          -photo-activation, 


          -ablation, ..... 



in an intuitive interface. Choose wavelength(s) and optical power... and: execute!!


You can start with a straightforward Firefly "point-and-shoot" single laser system which can be easily upgraded to 4 wavelengths; Led's or Lasers; medium or high power.


And, you can add the GEO system to it, allowing you to define your illumination patterns in an easy graphic software environment. With an intuitive user-interface, like in a movie editing program.

Timed, multi-pattern


You can easily program sequences where you can combine multiple patterns, and define the timing for each of the elements.

Local IP3 uncaging


A sample movie which shows three (Firefly) shots and their effect on the sample.

ChR2 activation


A sample movie which shows a GEO illumination followed by the optogenetic response.

Firefly webpage

GEO webpage

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Ca2+ waves evoked by local IP3 uncaging.

Courtesy of John McCarron, Strathclyde Institute of Pharmacy and Biomedical Sciences.

Firefly